Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 3/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556569 | 0.84 | KDM4E (0.40) | KMT2AMAPTKDM4EALPLPOLB | |
| SCHEMBL11557699 | 0.83 | TERT (0.40) | KMT2AF2KDM4EALPLPOLB | |
| SCHEMBL11560867 | 0.83 | KLKB1 (0.50) | KMT2AF2MAPTKDM4EALPL | |
| SCHEMBL12310841 | 0.83 | MMP2 (0.45) | KMT2AKDM4EALPLPOLBALDH1A1 | |
| SCHEMBL11559491 | 0.83 | KDR (0.51) | KMT2AF2MAPTKDM4EALPL | |
| SCHEMBL11559540 | 0.81 | ERN1 (0.38) | KMT2AKDM4EALPLPOLBMEN1 | |
| SCHEMBL11560143 | 0.81 | MAPT (0.40) | KMT2AMAPTKDM4EALPLPOLB | |
| SCHEMBL11560337 | 0.81 | MEN1 (0.54) | HSPD1HSPE1KMT2AMAPTKDM4E | |
| SCHEMBL11562864 | 0.80 | KLKB1 (0.53) | KMT2AMAPTKDM4EPOLBMEN1 | |
| SCHEMBL11559525 | 0.80 | CXCR2 (0.39) | KMT2AMAPTKDM4EALPLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |