Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892210 | 0.87 | JAK2 (0.55) | F2KDRJAK2TYK2POLB | |
| SCHEMBL11556569 | 0.84 | KDM4E (0.40) | ALOX15POLBHPGDMAPTKMT2A | |
| SCHEMBL12310841 | 0.83 | MMP2 (0.45) | KLKB1KDRPOLBHPGDKMT2A | |
| SCHEMBL11559144 | 0.83 | HSPD1 (0.40) | F2POLBHPGDMAPTKMT2A | |
| SCHEMBL11557699 | 0.83 | TERT (0.40) | KLKB1PLAUPLATP2RX1F2 | |
| SCHEMBL11559491 | 0.83 | KDR (0.51) | PLAUPLATP2RX1F2F10 | |
| SCHEMBL11559540 | 0.81 | ERN1 (0.38) | KLKB1KDRJAK2POLBKMT2A | |
| SCHEMBL11560143 | 0.81 | MAPT (0.40) | P2RX1KDRPOLBMAPTKMT2A | |
| SCHEMBL11562445 | 0.80 | RAB9A (0.45) | HPGDMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11559525 | 0.80 | CXCR2 (0.39) | POLBMAPTKMT2AKDM4EALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |