Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556569 | 0.87 | KDM4E (0.40) | TERTALPLKDM4EPOLBMEN1 | |
| SCHEMBL11560143 | 0.86 | MAPT (0.40) | TERTALPLKDM4EPOLBKDR | |
| SCHEMBL11559491 | 0.86 | KDR (0.51) | ALPLKDM4EPOLBKDRPLAU | |
| SCHEMBL11559540 | 0.84 | ERN1 (0.38) | TERTALPLKDM4EPOLBKDR | |
| SCHEMBL11560867 | 0.83 | KLKB1 (0.50) | ALPLKDM4EPOLBKDRPLAU | |
| SCHEMBL12310841 | 0.83 | MMP2 (0.45) | TERTALPLKDM4EPOLBKDR | |
| SCHEMBL11559144 | 0.83 | HSPD1 (0.40) | TERTALPLKDM4EPOLBF2 | |
| SCHEMBL11562864 | 0.83 | KLKB1 (0.53) | KDM4EPOLBKLKB1KLK1KLK5 | |
| SCHEMBL11562445 | 0.83 | RAB9A (0.45) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL11557497 | 0.83 | BRD4 (0.38) | TERTALPLKDM4EPOLBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | claimed |
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |