Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 6/20 | 0.33 |
| ▸ | ALPL | P05186 | 6/20 | 0.33 |
| ▸ | XIAP | P98170 | 6/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561756 | 0.85 | MAPT (0.38) | TSHRENPP3ALPLXIAPENPP1 | |
| SCHEMBL11558391 | 0.84 | GAA (0.39) | TSHRGAAALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11559781 | 0.81 | TSHR (0.38) | TSHRSMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL11565278 | 0.75 | TSHR (0.45) | TSHRENPP3ALPLXIAPENPP1 | |
| SCHEMBL10279632 | 0.74 | FAAH (0.41) | TSHRELANESMN1; SMN2ALDH1A1MCL1 | |
| SCHEMBL11558205 | 0.74 | ENPP3 (0.56) | ENPP3ALPLXIAPENPP1ELANE | |
| SCHEMBL9127491 | 0.73 | NOS1 (0.32) | TSHR | |
| SCHEMBL5272700 | 0.70 | ELANE (0.39) | TSHRELANESMN1; SMN2ALDH1A1 | |
| SCHEMBL19007302 | 0.68 | ALDH1A1 (0.65) | GAAALDH1A1 | |
| SCHEMBL17382016 | 0.67 | LMNA (0.46) | SMN1; SMN2GAAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153710-A | HYPOGLYCEMIC AGENTS | STAROGARDZKIE ZAKLADY FARMACEUTYCZNE POLFA (PL) | 1979-05-08 | — | — | US | disclosed |