Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565258 | 0.81 | CA12 (0.47) | CA12CA1CA2CA9SNCA | |
| SCHEMBL11069740 | 0.80 | RAB9A (0.50) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL8761357 | 0.78 | CASR (0.50) | CASRCA12CA1CA2CA9 | |
| SCHEMBL27791663 | 0.77 | HSD17B10 (0.48) | CA12CA9SMN1; SMN2LMNATSHR | |
| SCHEMBL11271388 | 0.75 | KCNJ6 (0.39) | CASRCA12CA1CA2CA9 | |
| SCHEMBL3033845 | 0.74 | PKM (0.58) | CASRSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL11060963 | 0.74 | ATAD2 (0.41) | CASRCA1CA2MEN1KMT2A | |
| SCHEMBL11057287 | 0.74 | MEN1 (0.43) | CASRCA1CA2CA9LMNA | |
| SCHEMBL6865288 | 0.74 | SNCA (0.72) | CASRCA12CA1CA2CA9 | |
| SCHEMBL10049716 | 0.73 | LMNA (0.60) | CASRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |