Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327887 | 0.80 | MMP8 (0.36) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL7829298 | 0.76 | ALDH1A1 (0.37) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL6557949 | 0.74 | PIN1 (0.44) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL16048 | 0.74 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL18759662 | 0.74 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL19278938 | 0.72 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL2238297 | 0.72 | PKM (0.41) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL413276 | 0.72 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL1450701 | 0.71 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1PKMKDM4E | |
| SCHEMBL4164631 | 0.71 | FDPS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166117-A | HYPOTENSIVES | SCIENCE UNION ET CIE (FR) | 1979-08-28 | — | — | US | disclosed |