Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566177 | 0.95 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL11563635 | 0.94 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL11561635 | 0.90 | RAB9A (0.63) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL22202128 | 0.81 | HPGD (0.70) | KMT2AHPGDKDM4EHDAC6HDAC1 | |
| SCHEMBL11563461 | 0.80 | NOS2 (0.58) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL11563180 | 0.80 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL6645913 | 0.79 | MAPT (0.53) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL10604098 | 0.78 | HCAR3 (0.59) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL11562872 | 0.78 | HCAR3 (0.68) | HPGDKDM4EHDAC1 | |
| SCHEMBL10737266 | 0.77 | HRH3 (0.47) | RAB9AKMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |