Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568628 | 0.87 | KAT6A (0.47) | NR1H4ALDH1A1THRBTSHRHSD17B10 | |
| SCHEMBL11559415 | 0.84 | GAA (0.54) | MAPK1ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL11565253 | 0.83 | LMNA (0.50) | MAPK1ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL11566344 | 0.83 | KMT2A (0.45) | MAPK1ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL6202473 | 0.80 | POLB (0.61) | MAPK1ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL11566902 | 0.78 | MAOB (0.53) | MAPK1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL11566910 | 0.76 | MAPK1 (0.49) | MAPK1NR1H4ALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL7533334 | 0.75 | ALDH1A1 (0.54) | MAPK1ALDH1A1GAA | |
| SCHEMBL11543631 | 0.73 | HPGD (0.60) | MAPK1ALDH1A1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL19019858 | 0.73 | NR1H4 (0.76) | MAPK1NR1H4HSD17B10L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |