Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 2/20 | 0.46 |
| ▸ | JUN | P05412 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566907 | 0.87 | MAPK1 (0.51) | POLBNR1H4L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11566344 | 0.85 | KMT2A (0.45) | KAT6AMAPTHPGDPOLBL3MBTL1 | |
| SCHEMBL11565253 | 0.85 | LMNA (0.50) | KAT6AMAPTHPGDPOLBL3MBTL1 | |
| SCHEMBL6202473 | 0.82 | POLB (0.61) | MAPTHPGDPOLBL3MBTL1TP53 | |
| SCHEMBL11559415 | 0.81 | GAA (0.54) | MAPTHPGDPOLBL3MBTL1TP53 | |
| SCHEMBL24376194 | 0.78 | HPGD (0.65) | KAT6AMAPTHPGDPOLBXBP1 | |
| SCHEMBL29969473 | 0.78 | HPGD (0.65) | KAT6AMAPTHPGDPOLBXBP1 | |
| SCHEMBL15751641 | 0.77 | KDM4E (0.51) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL7533334 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11568624 | 0.76 | MAOB (0.56) | MAPTHPGDPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |