Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.54 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985624 | 0.91 | NPFFR1 (0.62) | FAAHALDH1A1CYP2D6POLBNPFFR1 | |
| SCHEMBL3939085 | 0.90 | CYP2D6 (0.65) | FAAHALDH1A1CYP2D6LMNAPOLB | |
| SCHEMBL6045494 | 0.89 | NPFFR1 (0.61) | FAAHALDH1A1CYP2D6POLBNPFFR1 | |
| Hydrochloric Acid SCHEMBL11455282 | 0.89 | NPFFR1 (0.61) | FAAHALDH1A1CYP2D6POLBNPFFR1 | |
| Hydrochloric Acid SCHEMBL5240984 | 0.89 | NPFFR1 (0.61) | FAAHALDH1A1CYP2D6POLBNPFFR1 | |
| SCHEMBL11566758 | 0.88 | CA12 (0.55) | FAAHNPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL11566176 | 0.87 | FAAH (0.55) | FAAHALDH1A1CYP2D6NPFFR1NPFFR2 | |
| SCHEMBL11565880 | 0.87 | OPRM1 (0.57) | ALDH1A1CYP2D6LMNAPOLBNPFFR1 | |
| SCHEMBL7830278 | 0.86 | ALDH1A1 (0.63) | FAAHALDH1A1CYP2D6LMNANPFFR1 | |
| SCHEMBL11568366 | 0.86 | CYP2D6 (0.58) | FAAHALDH1A1CYP2D6POLBNPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |