Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132075 | 0.85 | DRD2 (0.48) | DRD2DRD3DRD4HTR7HTR2A | |
| SCHEMBL9130488 | 0.85 | DRD2 (0.46) | DRD2DRD3DRD4HTR7HTR1A | |
| SCHEMBL10752570 | 0.83 | HTR1A (0.54) | DRD2DRD3DRD4HTR7HTR2A | |
| SCHEMBL9131769 | 0.83 | DRD2 (0.44) | DRD2DRD3DRD4HTR7HTR2A | |
| SCHEMBL10749348 | 0.82 | KDM4E (0.47) | DRD2DRD3DRD4HTR7HTR2A | |
| SCHEMBL9131510 | 0.81 | DRD2 (0.45) | DRD2DRD3DRD4HTR7HTR2A | |
| SCHEMBL10744900 | 0.77 | HTR7 (0.44) | DRD3HTR7HTR1A | |
| SCHEMBL10758269 | 0.76 | DRD4 (0.47) | DRD2DRD3DRD4HTR1AADRA1A | |
| SCHEMBL11567096 | 0.75 | ADORA2A (0.36) | DRD2DRD3DRD4 | |
| SCHEMBL11674004 | 0.73 | SIGMAR1 (0.42) | DRD2DRD3DRD4HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179510-A | ISOCHROMANS AND 2-BENZOXEPINS | THE UPJOHN COMPANY (US) | 1979-12-18 | — | — | US | claimed |