Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570124 | 0.85 | KDM4E (0.46) | TSHRNPSR1ALDH1A1LMNACYP1A2 | |
| SCHEMBL11575467 | 0.81 | SMN1; SMN2 (0.41) | TAS1R3TAS1R1NPC1RAB9AALDH1A1 | |
| SCHEMBL11571517 | 0.79 | SMN1; SMN2 (0.39) | TAS1R3TAS1R1TSHRNPC1RAB9A | |
| SCHEMBL11568718 | 0.78 | NPC1 (0.48) | NPC1RAB9AMAPT | |
| SCHEMBL11649769 | 0.69 | KDM4E (0.47) | TSHRNPSR1NPC1ALDH1A1MEN1 | |
| SCHEMBL11573064 | 0.68 | ALDH1A1 (0.55) | ADRB2ADRB1TSHRNPSR1ALDH1A1 | |
| SCHEMBL11574023 | 0.67 | NPC1 (0.46) | NPC1RAB9A | |
| SCHEMBL11123663 | 0.65 | NPC1 (0.58) | TAS1R3TAS1R1NPC1RAB9AALDH1A1 | |
| SCHEMBL11570598 | 0.65 | MAPT (0.51) | ADRB2ADRB1TSHRNPC1RAB9A | |
| SCHEMBL4799916 | 0.64 | TAS1R3 (0.49) | TAS1R3TAS1R1NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |