Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568718 | 0.88 | NPC1 (0.48) | NPC1RAB9ATHRBPOLBMTNR1A | |
| SCHEMBL11571969 | 0.84 | ALDH1A1 (0.50) | NPC1RAB9APOLB | |
| SCHEMBL11569998 | 0.75 | MAPT (0.60) | NPC1RAB9A | |
| SCHEMBL11574421 | 0.75 | TDP1 (0.51) | NPC1RAB9ATHRBPOLBMTNR1A | |
| SCHEMBL11571517 | 0.74 | SMN1; SMN2 (0.39) | NPC1RAB9A | |
| SCHEMBL11575467 | 0.74 | SMN1; SMN2 (0.41) | NPC1RAB9APOLB | |
| SCHEMBL11570598 | 0.73 | MAPT (0.51) | NPC1RAB9ATHRBPOLBMTNR1A | |
| SCHEMBL11574037 | 0.71 | ALDH1A1 (0.52) | NPC1RAB9ATHRBPOLBMTNR1A | |
| SCHEMBL6560846 | 0.70 | LMNA (0.53) | MTNR1AMTNR1B | |
| SCHEMBL9463999 | 0.68 | LMNA (0.46) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |