Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571517 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL11568718 | 0.86 | NPC1 (0.48) | NPC1RAB9APOLBMAPT | |
| SCHEMBL11572479 | 0.83 | KDM4E (0.56) | SMN1; SMN2LMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL11569315 | 0.81 | ADRB2 (0.42) | SMN1; SMN2LMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL11574023 | 0.74 | NPC1 (0.46) | NPC1RAB9APOLB | |
| SCHEMBL11573154 | 0.72 | KDM4E (0.52) | SMN1; SMN2LMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL11572662 | 0.72 | KDM4E (0.49) | SMN1; SMN2LMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL11570598 | 0.71 | MAPT (0.51) | SMN1; SMN2KMT2ANPC1RAB9APOLB | |
| SCHEMBL11574037 | 0.71 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL18351234 | 0.70 | CA12 (0.45) | KMT2AALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |