Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.50 |
| ▸ | MME | P08473 | 5/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25927383 | 1.00 | KISS1R (0.50) | KISS1RMMESLC1A3SLC1A2TSHR | |
| SCHEMBL25927385 | 1.00 | KISS1R (0.50) | KISS1RMMESLC1A3SLC1A2TSHR | |
| SCHEMBL5672721 | 0.86 | KISS1R (0.61) | KISS1RMMESLC1A3SLC1A2CPA1 | |
| SCHEMBL27527680 | 0.83 | KISS1R (0.59) | KISS1RMMESLC1A3SLC1A2CPA1 | |
| Ammonia Solution, Strong SCHEMBL27748255 | 0.83 | KISS1R (0.59) | KISS1RMMESLC1A3SLC1A2CPA1 | |
| SCHEMBL3042219 | 0.80 | — | — | |
| SCHEMBL1257700 | 0.79 | SLC1A3 (0.58) | MMESLC1A3SLC1A2TSHRCPA1 | |
| SCHEMBL3657031 | 0.79 | KISS1R (0.50) | KISS1RMMESLC1A3SLC1A2TSHR | |
| SCHEMBL1257697 | 0.79 | SLC1A3 (0.58) | MMESLC1A3SLC1A2TSHRCPA1 | |
| Acetone SCHEMBL8844214 | 0.77 | LMNA (0.40) | KISS1RTSHRALDH1A1TDP1SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54148712-A | — | — | None | — | — | JP | disclosed |
| US-8993766-B2 | Method of preparing tetrabenazine and dihydrotetrabenazine | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-03-31 | — | — | US | disclosed |
| US-8993766-B2 | Method of preparing tetrabenazine and dihydrotetrabenazine | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-03-31 | — | — | US | disclosed |
| US-20140315790-A1 | AMINOTHIAZOLES AND THEIR USES | BUSHELL SIMON (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130252883-A1 | Macrocycles and Their Uses | NOVARTIS AG (CH) | 2013-09-26 | — | — | US | disclosed |
| US-20130197227-A1 | METHOD OF PREPARING TETRABENAZINE AND DIHYDROTETRABENAZINE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-08-01 | — | — | US | disclosed |
| US-8476224-B2 | Macrocycles and their uses | NOVARTIS AG (US) | 2013-07-02 | — | — | US | disclosed |
| JP-S54148712-A | PREPARATION OF ISOBUTYLACETONYLCARBINOL AND ISOAMYLIDENEACETONE | KURARAY CO LTD | 1979-11-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252883-A1 | Macrocycles and Their Uses | MRPL21, CLPP, MLEC | KISS1R 4405/4885MME 388/4885SLC1A3 4688/4885 |
| US-20130197227-A1 | METHOD OF PREPARING TETRABENAZINE AND DIHYDROTETRABENAZINE | TET1, TET3, DNMT1 | KISS1R 3662/4885MME 3750/4885SLC1A3 4829/4885 |
| US-20140315790-A1 | AMINOTHIAZOLES AND THEIR USES | ABAT, AADAT, GOT2 | KISS1R 4111/4885MME 497/4885SLC1A3 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.