Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501586 | 0.79 | DNM1 (0.36) | GNAI3GNAO1GNAI1SMN1; SMN2CYP2C19 | |
| Ipexidine SCHEMBL11468017 | 0.76 | GNAI3 (0.52) | USP2GNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL11575634 | 0.71 | USP2 (0.52) | USP2GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL11572940 | 0.70 | GNAI3 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11573567 | 0.68 | USP2 (0.37) | USP2GNAI3GNAO1GNAI1MMP3 | |
| SCHEMBL13756012 | 0.68 | KDM4E (0.50) | USP2KDM4EALDH1A1FPR3FPR2 | |
| SCHEMBL9683898 | 0.67 | ADH1B (0.47) | TP53MEN1KMT2A | |
| SCHEMBL18596029 | 0.67 | ADH1B (0.47) | TP53MEN1KMT2A | |
| SCHEMBL9252302 | 0.66 | ADH1B (0.50) | TP53MEN1KMT2A | |
| SCHEMBL11681448 | 0.66 | ADH1B (0.50) | TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |