Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.35 |
| ▸ | HTR3B | O95264 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144850 | 0.92 | NPC1 (0.46) | SIGMAR1CYP3A4ALDH1A1 | |
| SCHEMBL18741214 | 0.85 | CYP3A4 (0.41) | SIGMAR1LMNAIDO1CYP3A4HTR3E | |
| SCHEMBL3025013 | 0.82 | SIGMAR1 (0.36) | SIGMAR1LMNAIDO1CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9615764 | 0.80 | LMNA (0.37) | SIGMAR1LMNAIDO1CYP3A4ALDH1A1 | |
| SCHEMBL11502074 | 0.80 | SIGMAR1 (0.35) | SIGMAR1LMNAIDO1CYP3A4ALDH1A1 | |
| SCHEMBL11501939 | 0.79 | CYP3A4 (0.38) | SIGMAR1LMNACYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL11191152 | 0.76 | NPC1 (0.41) | CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL11801937 | 0.73 | MLYCD (0.41) | LMNAALDH1A1CYP2D6 | |
| SCHEMBL30338143 | 0.72 | SLC6A3 (0.33) | SIGMAR1 | |
| SCHEMBL10353146 | 0.72 | NPC1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016010984-A2 | COMPOSITIONS AND METHODS FOR TREATING ROSACEA | TISSUE TECH, INC. (US) | 2016-01-21 | — | — | WO | claimed |
| US-20160008295-A1 | COMPOSITIONS AND METHODS FOR TREATING ROSACEA | TISSUE TECH, INC. | 2016-01-14 | — | — | US | claimed |
| US-11931366-B2 | Compositions and methods of use thereof for treatment of proteinopathies | WASHINGTON UNIVERSITY (US) | 2024-03-19 | — | — | US | disclosed |
| US-20210228591-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES | WASHINGTON UNIVERSITY | 2021-07-29 | — | — | US | disclosed |
| CN-110573141-A | Concentrate of freshly squeezed plant juice of milfoil, its production and use | 西姆莱斯有限公司 | 2019-12-13 | — | — | CN | disclosed |
| WO-2019204764-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES | WASHINGTON UNIVERSITY (US) | 2019-10-24 | — | — | WO | disclosed |
| US-10155788-B2 | Cationic steroidal antimicrobial prodrug compositions and uses thereof | BRIGHAM YOUNG UNIVERSITY (US) | 2018-12-18 | — | — | US | disclosed |
| US-9827195-B2 | Fatty acid pharmaceutical foam | STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) | 2017-11-28 | — | — | US | disclosed |
| US-20160096864-A1 | CATIONIC STEROIDAL ANTIMICROBIAL PRODRUG COMPOSITIONS AND USES THEREOF | BRIGHAM YOUNG UNIVERSITY (US) | 2016-04-07 | — | — | US | disclosed |
| WO-2016010984-A2 | COMPOSITIONS AND METHODS FOR TREATING ROSACEA | TISSUE TECH, INC. (US) | 2016-01-21 | — | — | WO | disclosed |
| US-20160008295-A1 | COMPOSITIONS AND METHODS FOR TREATING ROSACEA | TISSUE TECH, INC. | 2016-01-14 | — | — | US | disclosed |
| US-20070059253-A1 | Foamable pharmaceutical compositions and methods for treating a disorder | STIEFEL LABORATORIES, INC. | 2007-03-15 | — | — | US | disclosed |
| US-7186416-B2 | Foamable pharmaceutical compositions and methods for treating a disorder | STIEFEL LABORATORIES, INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-20050232957-A1 | Compositions and methods for moisturizing skin | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 2005-10-20 | — | — | US | disclosed |
| US-20040241099-A1 | Foamable pharmaceutical compositions and methods for treating a disorder | CONNETICS CORPORATION | 2004-12-02 | — | — | US | disclosed |
| US-20040120990-A1 | Absorbent proteins and methods for using same | CUSHMAN JOHN C (US) | 2004-06-24 | — | — | US | disclosed |
| US-6547063-B1 | Article for the delivery of foam products | THE PROCTER & GAMBLE COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-6283336-B1 | Article for the delivery of foam products | THE PROCTER & GAMBLE COMPANY | 2001-09-04 | — | — | US | disclosed |
| EP-0189587-B1 | METHOD OF STERILIZING RECOMBINANT MICROORGANISM | SUNTORY LIMITED (JP) | 1989-12-13 | — | — | EP | disclosed |
| EP-0189587-A2 | Method of sterilizing recombinant microorganism | SUNTORY LIMITED (JP) | 1986-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11931366-B2 | Compositions and methods of use thereof for treatment of proteinopathies | SERPINA2, FABP1, TTR | SIGMAR1 1600/4885LMNA 403/4885IDO1 3940/4885 |
| US-10155788-B2 | Cationic steroidal antimicrobial prodrug compositions and uses thereof | CYP21A2, CYP11B1, CYP11B2 | SIGMAR1 929/4885LMNA 688/4885IDO1 1230/4885 |
| US-20210228591-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES | SERPINA2, FABP1, TTR | SIGMAR1 1600/4885LMNA 403/4885IDO1 3940/4885 |
| US-20160096864-A1 | CATIONIC STEROIDAL ANTIMICROBIAL PRODRUG COMPOSITIONS AND USES THEREOF | CYP21A2, CYP11B1, CYP11B2 | SIGMAR1 929/4885LMNA 688/4885IDO1 1230/4885 |
| US-20040241099-A1 | Foamable pharmaceutical compositions and methods for treating a disorder | CLN6, CYP27A1, CYP46A1 | SIGMAR1 3313/4885LMNA 1119/4885IDO1 4545/4885 |
| US-20070059253-A1 | Foamable pharmaceutical compositions and methods for treating a disorder | CLN6, CYP27A1, CYP46A1 | SIGMAR1 3313/4885LMNA 1119/4885IDO1 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.