Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15787156 | 0.85 | SMN1; SMN2 (0.48) | EPHX1EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL9612621 | 0.79 | NCF1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL15784672 | 0.77 | PARP1 (0.42) | KMT2AMEN1ALDH1A1PARP1 | |
| SCHEMBL13136091 | 0.76 | EPHX1 (0.56) | EPHX1EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL24744482 | 0.75 | L3MBTL1 (0.62) | EPHX1EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL11575424 | 0.75 | PABPC1 (0.46) | EPHX1EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL7283615 | 0.74 | KDM4E (0.33) | EPHX1EPHX2KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL18676271 | 0.74 | EPHX1 (0.54) | EPHX1EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL23986333 | 0.74 | EPHX2 (0.61) | EPHX1EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL1111914 | 0.72 | PABPC1 (0.47) | EPHX1EPHX2L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190015440-A1 | MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHY | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190015440-A1 | MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHY | SMN1; SMN2, UPF1, RBM17 | EPHX1 4680/4885EPHX2 4283/4885L3MBTL1 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.