SCHEMBL1157652

SCHEMBL1157652

O=S(=O)(O)Sc1ccc2ccccc2n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 5/20 0.51
PRNP P04156 5/20 0.51
KDM4E B2RXH2 2/20 0.51
NPSR1 Q6W5P4 4/20 0.49
ALDH1A1 P00352 4/20 0.49
MAPK10 P53779 2/20 0.49
RAB9A P51151 1/20 0.47
HPGD P15428 1/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
LMNA P02545 2/20 0.43
MGAM O43451 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
PTBP1 P26599 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR2 P34972 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
NCF1 P14598 1/20 0.39
NOS2 P35228 1/20 0.39
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2098479 0.73 RXFP1 (0.53) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL6899659 0.73 RXFP1 (0.53) RXFP1PRNPKDM4ENPSR1ALDH1A1
Sulfuric Acid SCHEMBL29378161 0.71 MGAM (0.47) RXFP1PRNPKDM4ENPSR1ALDH1A1
Sulfuric Acid SCHEMBL434092 0.71 MGAM (0.47) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL546320 0.71 MGAM (0.47) RXFP1PRNPKDM4EALDH1A1RAB9A
SCHEMBL2229163 0.70 PRNP (0.56) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL4370424 0.70 RXFP1 (0.50) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL2200585 0.70 NCF1 (0.52) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL11326601 0.70 RXFP1 (0.50) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL29979791 0.70 CYP1A2 (0.58) RXFP1PRNPKDM4ENPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888417-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2011-02-15 US disclosed
US-20080261722-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-10-23 US disclosed
US-20080227567-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-09-18 US disclosed
US-20080176678-A1 Compositions for Use in Golf Balls ACUSHNET COMPANY 2008-07-24 US disclosed
US-7361711-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-22 US disclosed
US-7358310-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358309-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358308-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-20060281586-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20060281587-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed