Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3066536 | 0.86 | MAPT (0.36) | L3MBTL1GAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28766985 | 0.79 | ALDH1A1 (0.36) | CES2CES1L3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL11579184 | 0.78 | ESR1 (0.33) | L3MBTL1GAAPARP10MAPTPARP1 | |
| SCHEMBL7184269 | 0.78 | KMT2A (0.38) | CES2CES1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11092653 | 0.77 | LMNA (0.38) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL3068495 | 0.76 | SIGMAR1 (0.49) | GAAALDH1A1 | |
| SCHEMBL15228984 | 0.76 | L3MBTL1 (0.36) | CES2CES1L3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL30883191 | 0.76 | L3MBTL1 (0.43) | CES2CES1L3MBTL1GAAKCNN4 | |
| SCHEMBL3542145 | 0.75 | CES2 (0.40) | CES2CES1L3MBTL1GAAKCNN4 | |
| SCHEMBL14053250 | 0.73 | CES2 (0.39) | CES2CES1L3MBTL1GAAKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |