Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11578654 | 0.84 | RAB9A (0.40) | RAB9ACYP1A2CYP2D6CYP2C19TMPRSS4 | |
| SCHEMBL11579869 | 0.83 | MAPT (0.47) | RAB9ACYP1A2CYP2D6CYP2C19TMPRSS4 | |
| SCHEMBL11581907 | 0.83 | RAB9A (0.58) | RAB9ACYP1A2CYP2D6CYP2C19TMPRSS4 | |
| SCHEMBL11807550 | 0.82 | OPRM1 (0.35) | RAB9ACYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL11053893 | 0.82 | RAB9A (0.43) | RAB9ACYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL11578514 | 0.81 | NPC1 (0.43) | RAB9ACYP1A2MAPTSMN1; SMN2F2 | |
| SCHEMBL4094802 | 0.80 | KDM4E (0.52) | RAB9ACYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL11580082 | 0.79 | ALDH1A1 (0.51) | TMPRSS4MAPTTP53F10PLAU | |
| SCHEMBL11581488 | 0.78 | MAPT (0.38) | RAB9AMAPTSMN1; SMN2PTGFRTP53 | |
| SCHEMBL11250945 | 0.78 | SIGMAR1 (0.51) | RAB9ACYP1A2CYP2D6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |