Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091737 | 0.89 | ALDH1A1 (0.40) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL11581667 | 0.85 | KMT2A (0.36) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL11579665 | 0.85 | KMT2A (0.36) | SLC2A1CA2CA12CA1CA9 | |
| SCHEMBL11262024 | 0.85 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11579652 | 0.83 | CYP1A2 (0.36) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL11583012 | 0.82 | RAB9A (0.35) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL11093554 | 0.82 | CYP1A2 (0.33) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL11096378 | 0.82 | RAPGEF4 (0.42) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11321311 | 0.82 | CA2 (0.40) | SLC2A1CA2CA12CA1CA9 | |
| SCHEMBL11877472 | 0.80 | SLC2A1 (0.34) | SLC2A1CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |