Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878500 | 0.84 | GAA (0.56) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11579736 | 0.84 | MAPT (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11579516 | 0.84 | MAPT (0.50) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11263800 | 0.84 | HTT (0.59) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11580880 | 0.84 | F10 (0.43) | MAPTMEN1KMT2ATDP1CXCR1 | |
| SCHEMBL11252215 | 0.83 | RORC (0.46) | MAPTKMT2AALDH1A1PKMRAB9A | |
| SCHEMBL11052550 | 0.81 | GAA (0.51) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL4107529 | 0.81 | HTT (0.56) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11093549 | 0.81 | PKM (0.66) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11580082 | 0.81 | ALDH1A1 (0.51) | GAAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |