Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 5/20 | 0.48 |
| ▸ | APEH | P13798 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289215 | 0.83 | ALDH1A1 (0.58) | PPME1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29289218 | 0.83 | ALDH1A1 (0.58) | PPME1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11563828 | 0.82 | PPME1 (0.47) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL11562973 | 0.82 | TRPA1 (0.57) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL11567151 | 0.80 | KDM4E (0.58) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL11557463 | 0.78 | LMNA (0.52) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL11560496 | 0.77 | PPME1 (0.55) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL11560494 | 0.77 | PPME1 (0.55) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL11564974 | 0.77 | MAPT (0.54) | PPME1APEHMEN1KMT2AALDH1A1 | |
| SCHEMBL3369333 | 0.74 | MAPT (0.63) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |