Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581587 | 0.78 | HTT (0.44) | CYP3A4ALDH1A1TDP1L3MBTL1GPR84 | |
| SCHEMBL8653857 | 0.77 | MAPK10 (0.44) | CYP3A4ALDH1A1L3MBTL1GPR84APOBEC3G | |
| SCHEMBL41241 | 0.76 | KDM1A (0.39) | LMNAALDH1A1TDP1OPRM1APOBEC3G | |
| SCHEMBL8656963 | 0.76 | ALDH1A1 (0.45) | CYP1A2LMNAALDH1A1TDP1OPRM1 | |
| SCHEMBL1468843 | 0.69 | NPC1 (0.41) | OPRM1MPOMAPT | |
| SCHEMBL5792155 | 0.69 | MMP2 (0.34) | CYP3A4LMNAALDH1A1TDP1OPRM1 | |
| SCHEMBL11580947 | 0.69 | ALDH1A1 (0.36) | CYP1A2CYP3A4LMNAALDH1A1TDP1 | |
| SCHEMBL4278697 | 0.68 | MPO (0.34) | LMNAALDH1A1OPRM1MPOPOLB | |
| SCHEMBL8952367 | 0.68 | ADRA1D (0.33) | CYP1A2ALDH1A1GPR84MEN1KMT2A | |
| SCHEMBL873253 | 0.68 | OPRM1 (0.32) | ALDH1A1OPRM1MPOPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088751-A | SHAVING CREAM, SHAMPOO, LOTION, 2-THIO-4-OXYPYRIMIDINE OR THIOHYDANTOIN AND HYDROGEN PEROXIDE, EXOTHERMIC REDOX REACTION | COLGATE-PALMOLIVE COMPANY (US) | 1978-05-09 | — | — | US | disclosed |