SCHEMBL115876

SCHEMBL115876

CCO[Si](CC)(OCC)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.34
TP53 P04637 2/20 0.33
MAPT P10636 1/20 0.32
RELA Q04206 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALDH1A1 P00352 3/20 0.31
TSHR P16473 3/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KCNH2 Q12809 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809337 0.90 LMNA (0.34) LTA4HALDH1A1HPGD
SCHEMBL3295855 0.90 TSHR (0.32) LTA4HTP53MAPTALDH1A1TSHR
SCHEMBL15209480 0.89
SCHEMBL704749 0.88 ESR1 (0.36) ESR1ESR2
SCHEMBL29066985 0.87 LTA4H (0.41) LTA4HTP53MAPTALDH1A1TSHR
SCHEMBL645725 0.86 LTA4H (0.34) LTA4HTP53MAPTRELANPSR1
SCHEMBL646940 0.86 LTA4H (0.34) LTA4HTP53MAPTRELANPSR1
SCHEMBL19816734 0.86 LTA4H (0.37) LTA4HTP53MAPTRELAALDH1A1
SCHEMBL706072 0.83 LMNA (0.37) LTA4HTP53ALDH1A1KDM4EHPGD
SCHEMBL707984 0.83 LTA4H (0.32) LTA4HTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025078379-A1 EASY TO CLEAN COATINGS WITH LOW FINGERPRINT VISIBILITY OPTITUNE OY (FI) 2025-04-17 WO claimed
CN-118546371-A Preparation method of photo-curing precursor of SiBOC ceramic and method for 3D printing SiBOC ceramic 哈尔滨工业大学 2024-08-27 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
US-10927219-B2 Crosslinked silsesquioxane random copolymers absorbing both UVA and UVB and method for preparing the same NANO AND MICRO TECHNOLOGIES CO., LTD. (KR) 2021-02-23 US claimed
US-20190202994-A1 CROSSLINKED SILSESQUIOXANE RANDOM COPOLYMERS ABSORBING BOTH UVA AND UVB AND METHOD FOR PREPARING THE SAME NANO AND MICRO TECHNOLOGIES CO., LTD. (KR) 2019-07-04 US claimed
US-20190169330-A1 Process For Producing High Cis-1,4-Polydiene With Lanthanide-Based Catalyst Compositions BRIDGESTONE CORPORATION (JP) 2019-06-06 US claimed
EP-3491030-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS Bridgestone Corporation (JP) 2019-06-05 EP claimed
US-10280355-B2 Reservoir wellbore fluid M-I L.L.C. (US) 2019-05-07 US claimed
EP-3340252-A1 ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
EP-1212380-A1 CHEMICALLY MODIFIED SILICA FILLERS, PROCESS FOR PRODUCING, AND SILICONE COMPOSITIONS CONTAINING SAME DOW CORNING CORPORATION (US) 2002-06-12 EP claimed
EP-1208165-A1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG Industries Ohio, Inc. (US) 2002-05-29 EP claimed
EP-1208164-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG Industries Ohio Inc. (US) 2002-05-29 EP claimed
US-6384125-B1 CONTACTING ACIDIC AQUEOUS SUSPENSION OF PRECIPITATED OR COLLOIDAL SILICA WITH COMBINATION OF FUNCTIONALIZING COUPLING AGENT AND ORGANOMETALLIC HYDROPHOBING COMPOUND, NEUTRALIZING TO INCREASE PH, RECOVERING MODIFIED FILLER DOW CORNING CORPORATION 2002-05-07 US claimed
WO-2001021715-A1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-03-29 WO claimed
WO-2001014480-A1 CHEMICALLY MODIFIED SILICA FILLERS, PROCESS FOR PRODUCING, AND SILICONE COMPOSITIONS CONTAINING SAME DOW CORNING CORPORATION (US) 2001-03-01 WO claimed
WO-2001012733-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO claimed
EP-0126186-B1 ELASTIC MOULDING COMPOSITION, METHOD FOR ITS PREPARATION AND MOULDING, AND ITS USE Degussa Aktiengesellschaft (DE) 1988-04-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927219-B2 Crosslinked silsesquioxane random copolymers absorbing both UVA and UVB and method for preparing the same XRCC5, ERCC5, XRCC6 LTA4H 951/4885TP53 1465/4885MAPT 1306/4885
US-20190202994-A1 CROSSLINKED SILSESQUIOXANE RANDOM COPOLYMERS ABSORBING BOTH UVA AND UVB AND METHOD FOR PREPARING THE SAME XRCC5, ERCC5, XRCC6 LTA4H 951/4885TP53 1465/4885MAPT 1306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.