SCHEMBL11596176

SCHEMBL11596176

CCC(CC)(CP(=O)(O)O)C(=O)NN

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.31
LAP3 P28838 1/20 0.31
MMP1 P03956 2/20 0.30
MMP2 P08253 2/20 0.30
MMP3 P08254 2/20 0.30
MMP8 P22894 2/20 0.30
MMP9 P14780 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12335973 0.80 CTSD (0.40) CTSDP2RX7
SCHEMBL11316221 0.80 MMP2 (0.34) MMP1MMP2MMP3MMP8MMP9
SCHEMBL11041745 0.77 LAP3 (0.34) LAP3
SCHEMBL26493020 0.76 CTSD (0.37) CTSD
SCHEMBL3044700 0.74 MEN1 (0.35) LAP3MMP1MMP2MMP3MMP8
SCHEMBL1691821 0.73 MMP1 (0.32) MMP1MMP2MMP3MMP8MMP9
SCHEMBL28013802 0.71 FDPS (0.34) MMP1MMP2MMP3MMP8MMP9
SCHEMBL12308746 0.69 MMP8 (0.37) CTSDMMP8
SCHEMBL7612809 0.69 FDPS (0.37) LAP3
SCHEMBL11595262 0.68 ANPEP (0.38) LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4125575-A Phosphonylated amides COMPAGNIE FRANCAISE DE PRODUITS INDUSTRIELS (FR) 1978-11-14 US claimed