Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713268 | 0.94 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBMAPTHTR6 | |
| SCHEMBL15460389 | 0.91 | LMNA (0.64) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL10451407 | 0.89 | LMNA (0.57) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL47890 | 0.89 | LMNA (0.67) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| (Phenylsulfonyl)Benzene SCHEMBL28185626 | 0.86 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2POLBMAPTHTR6 | |
| SCHEMBL8062016 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2POLBMAPTHTR6 | |
| SCHEMBL8046908 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2POLBMAPTHTR6 | |
| SCHEMBL15460390 | 0.85 | GAA (0.70) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL116485 | 0.85 | GAA (0.70) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL12792069 | 0.84 | LMNA (0.52) | ALDH1A1SMN1; SMN2POLBMAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| EP-4289894-A1 | RESIN COMPOSITION FOR ENCAPSULATING SEMICONDUCTOR ELEMENT-MOUNTED SURFACE OF SUBSTRATE WITH SEMICONDUCTOR ELEMENT MOUNTED THEREON OR SEMICONDUCTOR ELEMENT-FORMING SURFACE OF WAFER WITH SEMICONDUCTOR ELEMENT FORMED THEREON, AND USE THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-13 | — | — | EP | disclosed |
| WO-2021132279-A1 | RESIN COMPOSITION AND FILM | 株式会社カネカ | 2021-07-01 | — | — | WO | disclosed |
| WO-2020066595-A1 | PRODUCTION METHOD FOR METAL CLAD LAMINATE AND PRODUCTION METHOD FOR CIRCUIT BOARD | 日鉄ケミカル＆マテリアル株式会社 | 2020-04-02 | — | — | WO | disclosed |
| US-10438574-B2 | Sound absorbing and insulating material and method for manufacturing the same | HYUNDAI MOTOR COMPANY (KR) | 2019-10-08 | — | — | US | disclosed |
| US-9805707-B2 | Sound absorbing and insulating material and method for manufacturing the same | HYUNDAI MOTOR COMPANY (KR) | 2017-10-31 | — | — | US | disclosed |
| US-9805707-B2 | Sound absorbing and insulating material and method for manufacturing the same | HYUNDAI MOTOR COMPANY (KR) | 2017-10-31 | — | — | US | disclosed |
| WO-2017135897-A1 | A CATALYST FOR THE CARBONYLATION OF ALKENES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-08-10 | — | — | WO | disclosed |
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | disclosed |
| US-7540991-B2 | Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode | POLYMATECH CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7540991-B2 | Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode | POLYMATECH CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| EP-2006332-A1 | RESIN COMPOSITION AND METHOD FOR PRODUCING SAME | TEIJIN LIMITED (JP) | 2008-12-24 | — | — | EP | disclosed |
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | ALDH1A1 552/4885SMN1; SMN2 1701/4885POLB 4200/4885 |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | SFRP1, SOS1, FZD7 | ALDH1A1 1865/4885SMN1; SMN2 2404/4885POLB 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.