Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.68 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599735 | 0.84 | PAX8 (0.59) | ITGA4NAPEPLDPAX8HCRTR1BCHE | |
| SCHEMBL11601715 | 0.81 | MAOA (0.51) | ITGA4NAPEPLDPAX8BCHECNR1 | |
| SCHEMBL11621530 | 0.81 | ITGA4 (0.52) | ITGA4NAPEPLDPAX8HCRTR1BCHE | |
| SCHEMBL11600977 | 0.80 | ITGA4 (0.52) | ITGA4NAPEPLDPAX8HCRTR1BCHE | |
| SCHEMBL4652009 | 0.78 | CNR2 (0.75) | ITGA4NAPEPLDPAX8HCRTR1CNR1 | |
| SCHEMBL8340731 | 0.78 | MAPT (0.49) | ESR1MAOBKDM4EMEN1MAPT | |
| SCHEMBL11600019 | 0.77 | LMNA (0.47) | PTPN1MAOBKDM4EMEN1MAPT | |
| SCHEMBL11732399 | 0.77 | ALK (0.47) | ITGA4NAPEPLDPAX8BCHECNR2 | |
| SCHEMBL11547037 | 0.77 | CNR1 (0.62) | ITGA4NAPEPLDPAX8HCRTR1CNR1 | |
| SCHEMBL11550720 | 0.75 | CNR1 (0.67) | ITGA4NAPEPLDPAX8HCRTR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |