Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191950 | 0.83 | TDP1 (0.68) | CA1CA2LPAR1LPAR5TDP1 | |
| SCHEMBL4506078 | 0.80 | PTGS2 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5608673 | 0.79 | HPGD (0.62) | LPAR1LPAR5TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8746017 | 0.79 | LPAR1 (0.70) | CA1CA2LPAR1LPAR5ALDH1A1 | |
| SCHEMBL11604084 | 0.78 | LPAR1 (0.53) | LPAR1LPAR5TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11602631 | 0.78 | PARP10 (0.66) | CA1CA2LPAR1LPAR5ALDH1A1 | |
| SCHEMBL11603272 | 0.78 | LPAR1 (0.68) | CA1CA2LPAR1LPAR5ALDH1A1 | |
| SCHEMBL12767609 | 0.77 | PDCD1 (0.57) | PDCD1CD274CA12CA1CA2 | |
| Potassium Ion SCHEMBL11603948 | 0.76 | LPAR1 (0.52) | CA1CA2LPAR1LPAR5TDP1 | |
| SCHEMBL11602845 | 0.76 | CA2 (0.53) | CA1CA2LPAR1LPAR5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |