Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.50 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29971719 | 0.83 | REN (0.60) | LTA4HRENNLNCYP3A4SLC7A5 | |
| SCHEMBL28133942 | 0.83 | REN (0.60) | LTA4HRENNLNCYP3A4SLC7A5 | |
| SCHEMBL11479809 | 0.81 | LTA4H (0.53) | LTA4HRENNLNCYP3A4SLC7A5 | |
| SCHEMBL27826956 | 0.81 | AGTR2 (0.60) | LTA4HRENNLNCYP3A4SLC7A5 | |
| SCHEMBL30184773 | 0.81 | AGTR2 (0.60) | LTA4HRENNLNCYP3A4SLC7A5 | |
| SCHEMBL13563453 | 0.79 | REN (0.72) | REN | |
| SCHEMBL27719102 | 0.78 | CYP3A4 (0.58) | NLNCYP3A4SLC7A5 | |
| Bromide SCHEMBL27422846 | 0.78 | REN (0.58) | LTA4HREN | |
| Phenylalanine SCHEMBL28074950 | 0.78 | SLC7A5 (0.80) | LTA4HNLNCYP3A4SLC7A5 | |
| SCHEMBL11614133 | 0.78 | QPCT (0.49) | RENCYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100349-A | ANTIHISTAMINES | METCALF BRIAN WALTER | 1978-07-11 | — | — | US | disclosed |