Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788274 | 0.81 | MGLL (0.65) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL5726769 | 0.78 | ALDH1A1 (0.62) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL5727188 | 0.78 | ALDH1A1 (0.62) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL5726374 | 0.78 | ALDH1A1 (0.62) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL1164614 | 0.77 | PTGS2 (0.46) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL6789729 | 0.77 | KMT2A (0.62) | CA12CA1CA9KMT2ALMNA | |
| SCHEMBL59197 | 0.77 | PTGS2 (0.74) | LMNANFKB1PTGS2PTGS1CYP2C9 | |
| SCHEMBL11615277 | 0.76 | ALDH1A1 (0.51) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL6788185 | 0.76 | ALDH1A1 (0.56) | KMT2ALMNATP53SMN1; SMN2NFKB1 | |
| SCHEMBL6788699 | 0.75 | CCNA2 (0.55) | KMT2ALMNATP53SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | DCK, CCNK, CDK2 | CA12 4575/4885CA1 3961/4885CA9 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.