SCHEMBL1161600

SCHEMBL1161600

CCOC(=O)C(C)(C)CN

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.52
CYP4A11 Q02928 3/20 0.52
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 3/20 0.42
PKM P14618 3/20 0.40
CYP1A2 P05177 2/20 0.40
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MMP8 P22894 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
THRB P10828 1/20 0.38
ABCB11 O95342 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6264005 0.98 CYP4F2 (0.50) CYP4F2CYP4A11ALOX15ALDH1A1PKM
SCHEMBL26016142 0.83 CYP4F2 (0.35) CYP4F2CYP4A11LMNAHSD17B10KDM4E
SCHEMBL8212091 0.83 CYP4F2 (0.46) CYP4F2CYP4A11ALOX15ALDH1A1PKM
SCHEMBL22519700 0.82 CYP4F2 (0.58) CYP4F2CYP4A11ALOX15ALDH1A1PKM
Hydrochloric Acid SCHEMBL28096965 0.81 SOAT1 (0.52) CYP4F2CYP4A11ALOX15ALDH1A1PKM
SCHEMBL22922997 0.80 CYP4F2 (0.35) CYP4F2CYP4A11ALOX15ALDH1A1LMNA
Hydrochloric Acid SCHEMBL4768682 0.80 CYP4F2 (0.56) CYP4F2CYP4A11ALOX15ALDH1A1PKM
SCHEMBL2021436 0.80 CYP4F2 (0.67) CYP4F2CYP4A11ALOX15ALDH1A1PKM
SCHEMBL18363110 0.80 CYP4F2 (0.55) CYP4F2CYP4A11ALOX15ALDH1A1PKM
SCHEMBL130722 0.80 CYP4F2 (0.55) CYP4F2CYP4A11ALOX15ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184650-A 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof 中国人民解放军北部战区总医院 2024-06-14 CN claimed
CN-109232613-A For treating and preventing the condensed heteroaryl dihydro-pyrimidin of hepatitis b virus infected new 6- 豪夫迈·罗氏有限公司 2019-01-18 CN claimed
EP-3946460-B1 IMPROVED CONJUGATION LINKERS PROLYNX LLC (US) 2026-05-20 EP disclosed
US-20260007768-A1 CONJUGATION LINKERS PROLYNX LLC (US) 2026-01-08 US disclosed
EP-4608810-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS Septerna, Inc. (US) 2025-09-03 EP disclosed
US-12364771-B2 Conjugation linkers PROLYNX LLC (US) 2025-07-22 US disclosed
EP-4561575-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
CN-119970617-A Improved coupling joint 普罗林科斯有限责任公司 2025-05-13 CN disclosed
US-20250114460-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2025-04-10 US disclosed
EP-4384520-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2024-06-19 EP disclosed
CN-118184650-A 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof 中国人民解放军北部战区总医院 2024-06-14 CN disclosed
EP-0708768-A4 TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES SMITHKLINE BEECHAM CORP (US) 1996-08-21 EP disclosed
EP-0708768-A1 TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES SMITHKLINE BEECHAM CORPORATION (US) 1996-05-01 EP disclosed
US-5506240-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1996-04-09 US disclosed
EP-0443983-B1 Acyl compounds CIBA GEIGY AG (CH) 1996-02-28 EP disclosed
EP-0678503-A1 Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities CIBA-GEIGY AG (CH) 1995-10-25 EP disclosed
WO-1995002591-A1 TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES SMITHKLINE BEECHAM CORPORATION (US) 1995-01-26 WO disclosed
EP-0528762-A1 N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists CIBA-GEIGY AG (CH) 1993-02-24 EP disclosed
EP-0443983-A1 Acyl compounds CIBA-GEIGY AG (CH) 1991-08-28 EP disclosed
EP-0014997-B1 4-ARYLOXY- AND 4-ARYLTHIO-3-PHENYLPIPERIDINE DERIVATIVES, A PROCESS FOR THE PREPARATION OF SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007768-A1 CONJUGATION LINKERS OGFR, SLC43A1, ILK CYP4F2 1044/4885CYP4A11 1010/4885ALOX15 3551/4885
US-20250114460-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND PLK1, BUB1B, BUB1 CYP4F2 4659/4885CYP4A11 4119/4885ALOX15 3855/4885
US-12364771-B2 Conjugation linkers DNPEP, FGB, VIP CYP4F2 3234/4885CYP4A11 4429/4885ALOX15 4588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.