Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746132 | 0.92 | FAAH (0.65) | GAAFAAHNPC1RAB9ATP53 | |
| SCHEMBL12745808 | 0.86 | GAA (0.69) | GAAFAAHNPC1RAB9ATP53 | |
| SCHEMBL6656967 | 0.85 | FAAH (0.59) | GAAFAAHNPC1RAB9APDE4B | |
| SCHEMBL8845160 | 0.81 | NPC1 (0.74) | GAAFAAHNPC1RAB9AKMT2A | |
| SCHEMBL30563607 | 0.81 | GPR119 (0.65) | TP53MAPTKMT2APDE4B | |
| SCHEMBL19711151 | 0.79 | QDPR (0.61) | NPC1RAB9ATP53MAPTKMT2A | |
| SCHEMBL12745811 | 0.79 | FAAH (0.64) | GAAFAAHNPC1RAB9A | |
| SCHEMBL12352751 | 0.78 | ROCK2 (0.60) | GAAFAAHNPC1RAB9ATP53 | |
| SCHEMBL31717779 | 0.77 | GAA (0.57) | GAAFAAHNPC1RAB9AMAPT | |
| SCHEMBL14834075 | 0.77 | MGLL (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110459-A | ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4101663-A | ANTIHYPERTENSIVES | AMERICAN HOECHST CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4046900-A | TRANQUILIZERS, HYPOTENSIVES, ANALGESICS | AMERICAN HOECHST CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |