Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799216 | 0.91 | HTR1A (0.48) | HTR1AMAPTLMNAKDM4EMEN1 | |
| SCHEMBL8800063 | 0.87 | HTR1A (0.56) | HTR1ADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL11627928 | 0.84 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BHTR2B | |
| SCHEMBL11630910 | 0.83 | ADRA1D (0.58) | HTR1AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11630745 | 0.81 | ABCC1 (0.50) | HTR1ADRD2DRD1ADRA1DADRA1A | |
| SCHEMBL11630022 | 0.81 | ABCC1 (0.49) | HTR1ADRD2ADRA1DHTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL11634209 | 0.80 | ABCC1 (0.49) | HTR1ADRD2DRD1ADRA1DADRA1A | |
| SCHEMBL11629707 | 0.80 | HTR1A (0.60) | HTR1ADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL11633843 | 0.80 | ALDH1A1 (0.58) | HTR1AMAPTLMNAKDM4EMEN1 | |
| SCHEMBL11629833 | 0.78 | ADRA1D (0.48) | HTR1ADRD2ADRA1DHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | claimed |
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |