Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632481 | 0.91 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11631327 | 0.89 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11632587 | 0.80 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11629224 | 0.80 | DRD2 (0.56) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11633643 | 0.80 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11631389 | 0.80 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1LMNAMAPTDRD2 | |
| SCHEMBL11629904 | 0.80 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11631902 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11805624 | 0.79 | HTR7 (0.52) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL11633834 | 0.79 | CARM1 (0.47) | L3MBTL1ALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |