Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634992 | 0.91 | L3MBTL1 (0.53) | L3MBTL1OPRL1DRD2KDM4EALDH1A1 | |
| SCHEMBL11633475 | 0.90 | L3MBTL1 (0.45) | L3MBTL1OPRM1OPRL1CCR1DRD2 | |
| SCHEMBL11629569 | 0.87 | L3MBTL1 (0.44) | L3MBTL1CCR1DRD2KDM4EALDH1A1 | |
| SCHEMBL11629536 | 0.85 | SIGMAR1 (0.46) | L3MBTL1OPRL1CCR1DRD2ALDH1A1 | |
| SCHEMBL11630996 | 0.84 | SIGMAR1 (0.46) | L3MBTL1OPRL1CCR1DRD2ALDH1A1 | |
| SCHEMBL11629977 | 0.84 | SIGMAR1 (0.46) | L3MBTL1OPRL1CCR1DRD2ALDH1A1 | |
| SCHEMBL11629858 | 0.83 | L3MBTL1 (0.44) | L3MBTL1OPRM1OPRL1KDM4ELMNA | |
| SCHEMBL11629224 | 0.83 | DRD2 (0.56) | L3MBTL1DRD2KDM4EALDH1A1LMNA | |
| SCHEMBL11632587 | 0.83 | L3MBTL1 (0.50) | L3MBTL1DRD2KDM4EALDH1A1LMNA | |
| SCHEMBL11630316 | 0.82 | OPRM1 (0.52) | L3MBTL1OPRM1OPRL1CCR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |