Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633695 | 0.88 | ESR1 (0.41) | PTPN1PTPN2PTPN6LMNAHNF4A | |
| SCHEMBL11630841 | 0.83 | RNASEH1 (0.42) | PTPN1PTPN2PTPN6LMNAHNF4A | |
| SCHEMBL13850877 | 0.81 | HNF4A (0.54) | PTPN1PTPN2PTPN6HNF4AKDM4E | |
| SCHEMBL16019088 | 0.79 | PLA2G10 (0.42) | PTPN1PTPN2PTPN6LMNAHNF4A | |
| SCHEMBL480096 | 0.79 | GABRP (0.40) | LMNAHCAR2KDM4ECYP1A2MAPT | |
| SCHEMBL13851064 | 0.77 | KDM4E (0.48) | LMNAKDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL924382 | 0.77 | HNF4A (0.50) | PTPN1PTPN2PTPN6LMNAHNF4A | |
| SCHEMBL13851063 | 0.75 | KDM4E (0.46) | PTPN1PTPN2PTPN6HNF4AKDM4E | |
| SCHEMBL12358956 | 0.74 | LMNA (0.47) | LMNAHNF4AALDH1A1HPGDHTT | |
| SCHEMBL14065327 | 0.74 | KDM4E (0.47) | LMNAKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109000-A | HYPOTENSIVES | NIPPON SHINYAKU CO., LTD. (JP) | 1978-08-22 | — | — | US | claimed |