Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.35 |
| ▸ | TUBB | P07437 | 5/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163118 | 0.87 | HTR6 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL1163103 | 0.87 | MTNR1A (0.44) | MTNR1AMTNR1BPDE4BPDE4APDE4C | |
| SCHEMBL1163237 | 0.84 | ABCB1 (0.34) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1163174 | 0.82 | MTNR1A (0.40) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL1163435 | 0.77 | MTNR1A (0.40) | MTNR1AMTNR1BPDE4BPDE4APDE4C | |
| SCHEMBL1163371 | 0.70 | TAAR1 (0.38) | MTNR1AMTNR1B | |
| SCHEMBL1162983 | 0.70 | ADRB2 (0.39) | MTNR1AMTNR1B | |
| SCHEMBL4399980 | 0.69 | HTR6 (0.44) | — | |
| Hydrochloric Acid SCHEMBL4399229 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL29546745 | 0.65 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342054-A1 | COMPOUNDS AND METHODS OF USE THEREOF | ELDER AMY (US) | 2017-11-30 | — | — | US | disclosed |
| US-20170342054-A1 | COMPOUNDS AND METHODS OF USE THEREOF | ELDER AMY (US) | 2017-11-30 | — | — | US | disclosed |
| US-20170342054-A1 | COMPOUNDS AND METHODS OF USE THEREOF | ELDER AMY (US) | 2017-11-30 | — | — | US | disclosed |
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2015-10-08 | — | — | US | disclosed |
| US-8912220-B2 | Compounds and methods of use thereof | Galenea Pharmaceuticals | 2014-12-16 | — | — | US | disclosed |
| US-8912220-B2 | Compounds and methods of use thereof | Galenea Pharmaceuticals | 2014-12-16 | — | — | US | disclosed |
| US-8912220-B2 | Compounds and methods of use thereof | Galenea Pharmaceuticals | 2014-12-16 | — | — | US | disclosed |
| EP-2464227-A1 | COMPOUNDS AND METHODS OF USE THEREOF | Galenea Corporation (US) | 2012-06-20 | — | — | EP | disclosed |
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION | 2011-06-16 | — | — | US | disclosed |
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION | 2011-06-16 | — | — | US | disclosed |
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION | 2011-06-16 | — | — | US | disclosed |
| WO-2011019738-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011019738-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342054-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | MTNR1A 65/4885MTNR1B 36/4885PDE4B 265/4885 |
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | MTNR1A 65/4885MTNR1B 36/4885PDE4B 265/4885 |
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | MTNR1A 65/4885MTNR1B 36/4885PDE4B 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.