Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11610757 | 0.81 | NR1I2 (0.58) | PTGS2CASRNR1I2EGFRADRA2A | |
| SCHEMBL6872385 | 0.80 | MAPT (0.53) | ALDH1A1 | |
| SCHEMBL11609021 | 0.80 | CASR (0.45) | PTGS2CASRNR1I2EGFRADRA2A | |
| SCHEMBL11166292 | 0.79 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL11608488 | 0.78 | HPGD (0.53) | PTGS2NR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11606364 | 0.78 | L3MBTL1 (0.67) | EGFRALDH1A1 | |
| SCHEMBL11602843 | 0.77 | CASR (0.68) | CASRPDE3AALDH1A1 | |
| SCHEMBL11635950 | 0.77 | DHODH (0.45) | PTGS2CASRNR1I2EGFRADRA2A | |
| SCHEMBL11608433 | 0.76 | FNTA (0.48) | PTGS2CASRNR1I2EGFRADRA2A | |
| SCHEMBL11793733 | 0.75 | EPHX2 (0.38) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |