Sulfotep

Sulfotep

SCHEMBL9401149

CCOP(=S)(OCC)OP(=S)(OCC)OCC.O=C(O)COCC(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PPARD Q03181 1/20 0.32
GLA P06280 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 4/20 0.31
ALDH1A1 P00352 3/20 0.31
KDM4E B2RXH2 1/20 0.31
MVD P53602 1/20 0.31
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CTH P32929 1/20 0.30
CBS P35520 1/20 0.30
THPO P40225 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfotep SCHEMBL7762968 0.85 FFAR3 (0.46) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL1163901 0.85 FFAR3 (0.46) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL461502 0.85 TDP1 (0.39) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL9651631 0.83 PPARD (0.39) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL11232718 0.83 MEN1 (0.38) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL5016573 0.83 MEN1 (0.38) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL11233341 0.81 MEN1 (0.36) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL53003 0.81 ALOX15 (0.37) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL7767701 0.80 FFAR3 (0.52) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL1163295 0.80 FFAR3 (0.52) MEN1KMT2ATDP1PPARDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5277206-A Pre-fixing by applying dithio compound; resilience, elasticity GOLDWELL AG (DE) 1994-01-11 US claimed
US-5277206-A Pre-fixing by applying dithio compound; resilience, elasticity GOLDWELL AG (DE) 1994-01-11 US disclosed