Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642260 | 0.87 | L3MBTL1 (0.50) | KMT2AMEN1TSHRAKR1C1CYP2C19 | |
| SCHEMBL23261664 | 0.82 | GLA (0.51) | KMT2AMEN1TSHRAKR1C1CYP2C19 | |
| SCHEMBL7464907 | 0.79 | L3MBTL1 (0.55) | KMT2AMEN1AKR1C1LMNAOPRK1 | |
| SCHEMBL6669616 | 0.77 | THRB (0.47) | KMT2AMEN1TSHRTHRBMAPT | |
| SCHEMBL9359055 | 0.75 | CYP2C9 (0.45) | KMT2AMEN1THRBCYP1A2CYP2C9 | |
| SCHEMBL3443849 | 0.75 | L3MBTL1 (0.51) | KMT2AMEN1AKR1C1LMNAOPRK1 | |
| SCHEMBL23163980 | 0.75 | FAAH (0.48) | KMT2AMEN1TSHRAKR1C1 | |
| SCHEMBL4606853 | 0.74 | KMT2A (0.73) | KMT2AMEN1TSHRTHRBAKR1C1 | |
| SCHEMBL19405089 | 0.74 | HTR1D (0.53) | KMT2AMEN1TSHRLMNAALDH1A1 | |
| SCHEMBL1465128 | 0.73 | SIGMAR1 (0.50) | KMT2AAKR1C1LMNAOPRK1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130559-A | BACTERICIDES | TSINKER MAIA G | 1978-12-19 | — | — | US | disclosed |