SCHEMBL11648239

SCHEMBL11648239

OC1([SiH2]c2ccccc2)CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.32
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251108 0.75 TRPA1 (0.30) MEN1POLBKMT2A
SCHEMBL7839459 0.75 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL10937384 0.75 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL999023 0.75 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL28060933 0.71 DPP4 (0.40)
SCHEMBL9270158 0.71
SCHEMBL8087905 0.71
SCHEMBL6536454 0.71 ALDH1A1 (0.31)
SCHEMBL3258571 0.71 MEN1 (0.31) MEN1POLBKMT2A
SCHEMBL9302212 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4068919-A POLYSILOXANES, WAVEGUIDES THOMSON-CSF (FR) 1978-01-17 US claimed
US-4068919-A POLYSILOXANES, WAVEGUIDES THOMSON-CSF (FR) 1978-01-17 US disclosed
US-4068919-A POLYSILOXANES, WAVEGUIDES THOMSON-CSF (FR) 1978-01-17 US disclosed