SCHEMBL3258571

SCHEMBL3258571

CC(C)C1([SiH2]c2ccccc2)CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251108 0.75 TRPA1 (0.30) MEN1POLBKMT2A
SCHEMBL10937384 0.71 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL11648239 0.71 AKR1C1 (0.32) MEN1POLBKMT2A
SCHEMBL999023 0.71 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL7839459 0.71 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL28161535 0.71
SCHEMBL9270158 0.71
SCHEMBL6536454 0.71 ALDH1A1 (0.31) ALDH1A1TSHRL3MBTL1
SCHEMBL27866604 0.70
SCHEMBL8087905 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6387855-B1 FOR KERATIN FIBERS L'OREAL S.A. (FR) 2002-05-14 US claimed
EP-3715927-B1 FIRE RESISTANT OPTICAL FIBRE CABLE WITH HIGH FIBRE COUNT PRYSMIAN SPA (IT) 2022-06-15 EP disclosed
EP-3715927-A1 FIRE RESISTANT OPTICAL FIBRE CABLE WITH HIGH FIBRE COUNT Prysmian S.p.A. (IT) 2020-09-30 EP disclosed
US-10294352-B2 Curable, highly transparent silicone composition with improved mechanics, for optical components WACKER CHEMIE AG (DE) 2019-05-21 US disclosed
US-20170321039-A1 CURABLE, HIGHLY TRANSPARENT SILICONE COMPOSITION WITH IMPROVED MECHANICS, FOR OPTICAL COMPONENTS WACKER CHEMIE AG (DE) 2017-11-09 US disclosed
US-20100061953-A1 METHOD FOR THE COSMETIC TREATMENT OF KERATINIC MATERIALS AND COMPOSITION CONTAINING A GRAFTED AMINO ACID POLYMER L'OREAL S.A. (FR) 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100061953-A1 METHOD FOR THE COSMETIC TREATMENT OF KERATINIC MATERIALS AND COMPOSITION CONTAINING A GRAFTED AMINO ACID POLYMER KRT18, CUTA, AADAT MEN1 1783/4885POLB 962/4885KMT2A 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.