SCHEMBL116485

SCHEMBL116485

Cc1ccc(S(=O)(=O)c2ccc(C)c(C)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.70
RAPGEF4 Q8WZA2 2/20 0.59
TDP1 Q9NUW8 2/20 0.57
LMNA P02545 1/20 0.57
ALDH1A1 P00352 4/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
POLB P06746 1/20 0.52
PKM P14618 3/20 0.51
HTT P42858 2/20 0.48
CA2 P00918 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460390 1.00 GAA (0.70) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL15460389 0.93 LMNA (0.64) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL47890 0.91 LMNA (0.67) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL4638498 0.85 ALDH1A1 (0.70) GAATDP1LMNAALDH1A1MAPT
SCHEMBL11947067 0.85 TDP1 (0.55) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL170033 0.83 GAA (1.00) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL5146968 0.83 ALDH1A1 (0.67) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL4400955 0.83 GAA (1.00) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL10067072 0.83 GAA (1.00) GAARAPGEF4TDP1LMNAALDH1A1
SCHEMBL10450168 0.83 LMNA (0.57) GAATDP1LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228704-A1 MELT-PROCESSABLE POLYIMIDES WITH HIGH GLASS TRANSITION TEMPERATURE EVONIK FIBRES GMBH (AT) 2024-07-11 US disclosed
US-20240228704-A1 MELT-PROCESSABLE POLYIMIDES WITH HIGH GLASS TRANSITION TEMPERATURE EVONIK FIBRES GMBH (AT) 2024-07-11 US disclosed
CN-116496136-A Diaryl sulfone compound and preparation method thereof 华北水利水电大学 2023-07-28 CN disclosed
EP-2880080-B1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PROD & CHEM (US) 2018-07-04 EP disclosed
US-9969845-B2 Hydroxyl-containing poly(alkylene phosphates) LANXESS DEUTSCHLAND GMBH (DE) 2018-05-15 US disclosed
US-9920081-B2 Halogen-free poly(alkylene phosphates) LANXESS DEUTSCHLAND GMBH (DE) 2018-03-20 US disclosed
US-20160215101-A1 HYDROXYL-CONTAINING POLY(ALKYLENE PHOSPHATES) LANXESS DEUTSCHLAND GMBH (DE) 2016-07-28 US disclosed
US-20150080276-A1 PHOSPHORIC ESTER PREPARATIONS WITH REDUCED HYGROSCOPICITY LANXESS DEUTSCHLAND GMBH (DE) 2015-03-19 US disclosed
US-8846967-B2 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2014-09-30 US disclosed
US-8821617-B2 Polyimide-co-polybenzoxazole copolymer, preparation method thereof, and gas separation membrane comprising the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2014-09-02 US disclosed
US-20120184766-A1 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2012-07-19 US disclosed
US-20120184765-A1 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2012-07-19 US disclosed
US-20120184764-A1 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2012-07-19 US disclosed
US-20120058358-A1 Flame-retardant timber materials LANXESS DEUTSCHLAND GMBH (DE) 2012-03-08 US disclosed
US-7989037-B2 A layer of discotic liquid-crystal and an anisotropic fluoropolymer of acrylic esters, e.g., 4-((4-nitrilophenoxy)butyl acrylate /2-(perfluorhexyl)ethyl acrylate copolymer; providing stability/optical compensation; no defects from optical fluctuation or alignment failure; controlling the tilt angle FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed
US-20080090027-A1 Composition, retardation plate, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-4778932-A Process for preparing diarylsulfones NEW JAPAN CHEMICAL CO., LTD. (JP) 1988-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184764-A1 Process for preparing alkyl phosphates PNKP, PHOSPHO1, DCTPP1 GAA 1783/4885RAPGEF4 148/4885TDP1 1821/4885
US-20120184766-A1 Process for preparing alkyl phosphates PHOSPHO1, PNKP, PLCB3 GAA 1393/4885RAPGEF4 129/4885TDP1 1594/4885
US-20120184765-A1 Process for preparing alkyl phosphates PNKP, PHOSPHO1, DCTPP1 GAA 1783/4885RAPGEF4 148/4885TDP1 1821/4885
US-20120058358-A1 Flame-retardant timber materials PFAS, CYP4F3, TARS2 GAA 3197/4885RAPGEF4 1502/4885TDP1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.