⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891523 | 0.88 | — | — | |
| SCHEMBL4263383 | 0.83 | — | — | |
| SCHEMBL7799148 | 0.81 | OPRM1 (0.39) | — | |
| SCHEMBL3475 | 0.81 | — | — | |
| SCHEMBL3899908 | 0.78 | DNM1 (0.36) | — | |
| SCHEMBL267594 | 0.75 | PRKCA (0.34) | — | |
| SCHEMBL9848963 | 0.75 | PRKCA (0.34) | — | |
| SCHEMBL4274138 | 0.74 | LMNA (0.39) | — | |
| SCHEMBL19546012 | 0.73 | PRKCA (0.33) | — | |
| SCHEMBL8357678 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846915-B2 | Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester | AUROBINDO PHARMA LTD. (IN) | 2014-09-30 | — | — | US | claimed |
| US-8759518-B2 | Intermediates for the preparation of HMG CoA reductase inhibitors and processes for the preparation thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-06-24 | — | — | US | claimed |
| US-20130158263-A1 | INTERMEDIATES FOR THE PREPARATION OF HMG COA REDUCTASE INHIBITORS AND PROCESSES FOR THE PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2013-06-20 | — | — | US | claimed |
| EP-2467363-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | Aurobindo Pharma Limited (IN) | 2012-06-27 | — | — | EP | claimed |
| US-20120149905-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | AUROBINDO PHARMA LTD (IN) | 2012-06-14 | — | — | US | claimed |
| WO-2011104725-A2 | HMG-COA REDUCTASE INHIBITORS AND PROCESS FOR THE PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-09-01 | — | — | WO | claimed |
| WO-2011021058-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | AUROBINDO PHARMA LIMITED (IN) | 2011-02-24 | — | — | WO | claimed |
| WO-2009118598-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM WITH HIGH PURITY | AUROBINDO PHARMA LIMITED (IN) | 2009-10-01 | — | — | WO | claimed |
| US-7091290-B2 | Method for preparing homo-and co-polymers of cyclic olefin compounds using an organic boron compound as a catalyst activator | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2006-08-15 | — | — | US | claimed |
| US-20050245703-A1 | addition polymerization of nonaromatic cyclic olefins, such as alkylnorbornenes and dicyclopentadienes, in the presence of a catalyst complex also including a nickel II carboxylate and an aluminoxane compound; high molecular weight polymer in high yields; gelation inhibition | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2005-11-03 | — | — | US | claimed |
| US-8846915-B2 | Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester | AUROBINDO PHARMA LTD. (IN) | 2014-09-30 | — | — | US | disclosed |
| US-8759518-B2 | Intermediates for the preparation of HMG CoA reductase inhibitors and processes for the preparation thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-06-24 | — | — | US | disclosed |
| US-20130158263-A1 | INTERMEDIATES FOR THE PREPARATION OF HMG COA REDUCTASE INHIBITORS AND PROCESSES FOR THE PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2013-06-20 | — | — | US | disclosed |
| US-8399570-B2 | Functionalized polymers and improved tires therefrom | BRIDGESTONE CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| WO-2012140490-A2 | PROCESS FOR PREPARING QUINOLINE DERIVATIVE | AUROBINDO PHARMA LIMITED (IN) | 2012-10-18 | — | — | WO | disclosed |
| EP-0808849-A1 | Process for the production of ethylenic polymers | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-11-26 | — | — | EP | disclosed |
| US-5369109-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0475627-B1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEM RES (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5276154-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0475627-A1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-03-18 | — | — | EP | disclosed |