Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218213 | 0.90 | SMN1; SMN2 (0.50) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNN4 | |
| SCHEMBL29420719 | 0.90 | SMN1; SMN2 (0.50) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNN4 | |
| SCHEMBL381604 | 0.88 | SMN1; SMN2 (0.49) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNN4 | |
| SCHEMBL28203916 | 0.87 | SMN1; SMN2 (0.41) | ADRA2AADRA2BADRA2CNISCHSMN1; SMN2 | |
| SCHEMBL27845912 | 0.86 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CNISCHSMN1; SMN2 | |
| SCHEMBL23243404 | 0.84 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CNISCHSMN1; SMN2 | |
| SCHEMBL28203874 | 0.84 | TDO2 (0.45) | ADRA2AADRA2BADRA2CNISCHSMN1; SMN2 | |
| SCHEMBL21351777 | 0.84 | KCNN4 (0.47) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNN4 | |
| SCHEMBL84185 | 0.84 | KCNN4 (0.47) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNN4 | |
| SCHEMBL9566190 | 0.82 | KCNN4 (0.46) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169289-B1 | METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-29 | — | — | EP | claimed |
| CN-1341092-A | Process for producing derivatives of biphenyl-2-carboxylic acid | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-03-20 | — | — | CN | claimed |
| CN-113518811-B | Easy-to-adhere polyester film | 东洋纺株式会社 | 2024-01-02 | — | — | CN | disclosed |
| CN-114174427-B | Flame retardant polybutylene terephthalate resin composition | 宝理塑料株式会社 | 2023-08-15 | — | — | CN | disclosed |
| CN-114391032-A | Polyester resin composition and molded article thereof | 东丽先端材料研究开发（中国）有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114174427-A | Flame-retardant polybutylene terephthalate resin composition | 宝理塑料株式会社 | 2022-03-11 | — | — | CN | disclosed |
| CN-113518811-A | Easily adhesive polyester film | 东洋纺株式会社 | 2021-10-19 | — | — | CN | disclosed |
| WO-2021140565-A1 | FLAME-RETARDANT POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION | ポリプラスチックス株式会社 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021020095-A1 | FLAME-RETARDANT POLY(BUTYLENE TEREPHTHALATE) RESIN COMPOSITION | ポリプラスチックス株式会社 | 2021-02-04 | — | — | WO | disclosed |
| WO-2021014922-A1 | READILY ADHERABLE POLYESTER FILM | 東洋紡株式会社 | 2021-01-28 | — | — | WO | disclosed |
| EP-2199456-B1 | POLYESTER FIBER, PROCESS FOR PRODUCING THE SAME, AND TEXTILE STRUCTURE EMPLOYING THE SAME | TORAY INDUSTRIES (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-6369271-B1 | SAPONIFICATION WITH HYDROCHLORIC ACID, HEATING WITH PRESSURIZATION | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-04-09 | — | — | US | disclosed |
| CN-1341092-A | Process for producing derivatives of biphenyl-2-carboxylic acid | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-03-20 | — | — | CN | disclosed |
| US-6225345-B1 | FOR THERAPY OF ACQUIRED IMMUNODEFICIENCY SYNDROME | NOVARTIS AG (CH) | 2001-05-01 | — | — | US | disclosed |
| WO-1999006398-A1 | 1,3-OXAZOLINYL-BIPHENYL DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 1999-02-11 | — | — | WO | disclosed |
| EP-0876336-A1 | AZAHEXANE DERIVATIVES AS SUBSTRATE ISOSTERS OF RETROVIRAL ASPARATE PROTEASES | Novartis AG (CH) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997019055-A1 | AZAHEXANE DERIVATIVES AS SUBSTRATE ISOSTERS OF RETROVIRAL ASPARATE PROTEASES | NOVARTIS AG (CH) | 1997-05-29 | — | — | WO | disclosed |
| US-5382666-A | Heterocyclic intermediates | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| WO-1994015926-A1 | ANGIOTENSIN II INHIBITORS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-07-21 | — | — | WO | disclosed |
| US-5256658-A | Biphenylyl tetrazoles for hypertension in mammals | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |