Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671871 | 0.91 | MAPT (0.42) | RAB9ANPC1JAK2ALDH1A1HTT | |
| SCHEMBL11671621 | 0.90 | POLB (0.40) | RAB9ANPC1PPARGALDH1A1HTT | |
| SCHEMBL11670918 | 0.90 | ACACB (0.41) | RAB9ANPC1PPARGALDH1A1HTT | |
| SCHEMBL11672045 | 0.89 | PPARG (0.42) | RAB9ANPC1PPARGLTB4R2TP53 | |
| SCHEMBL11670507 | 0.89 | HSD17B1 (0.43) | RAB9ANPC1ALDH1A1HTTPAX8 | |
| SCHEMBL11670431 | 0.88 | MTNR1B (0.44) | ALDH1A1LTA4H | |
| SCHEMBL11670901 | 0.88 | MAOB (0.39) | ALDH1A1TP53MAPTACACBACACA | |
| SCHEMBL11671052 | 0.88 | TP53 (0.40) | RAB9ANPC1PPARGJAK2ALDH1A1 | |
| SCHEMBL11671665 | 0.87 | GAA (0.46) | RAB9ANPC1ALDH1A1HTTTP53 | |
| SCHEMBL11670409 | 0.86 | LMNA (0.40) | ALDH1A1HTTTP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |