Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677605 | 0.90 | SRC (0.73) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL11680362 | 0.88 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL28033698 | 0.86 | SRC (0.54) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL271454 | 0.86 | SRC (0.43) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL11679477 | 0.81 | KMT2A (0.60) | SRCLMNAALDH1A1KMT2A | |
| SCHEMBL8559192 | 0.81 | SRC (0.48) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL11275550 | 0.80 | L3MBTL1 (0.53) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL11076351 | 0.80 | SRC (0.47) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL237104 | 0.79 | TDP1 (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL5458091 | 0.78 | MMP8 (0.66) | SRCTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288258-A1 | CROSSLINKED POLYAMIDE | BASF SE (DE) | 2011-11-24 | — | — | US | disclosed |
| CN-101838218-A | Ester compound and pharmaceutical use of the same | JAPAN TOBACCO INC | 2010-09-22 | — | — | CN | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| CN-1630629-B | Ester compound and medical use thereof | JAPAN TOBACCO INC | 2010-05-05 | — | — | CN | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| CN-1943786-A | Ester compound and its medicinal application | JAPAN TOBACCO INC (JP) | 2007-04-11 | — | — | CN | disclosed |
| US-20060205726-A1 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | disclosed |
| CN-1630629-A | Ester compound and medical use thereof | JAPAN TOBACCO INC (JP) | 2005-06-22 | — | — | CN | disclosed |
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1479666-A1 | ESTER COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-11-24 | — | — | EP | disclosed |
| EP-0238982-A1 | Anticholinergic compounds, pharmaceutical compositions and method of treatment | UNIVERSITY OF FLORIDA (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4072710-A | FROM SILYL ESTER AND THIONYL CHLORIDE | PALOMO COLL A L | 1978-02-07 | — | — | US | disclosed |
| US-4038253-A | PHOTOCROSS-LINKABLE POLYMERS CONTAINING PENDANT DIAZOESTER GROUPS | HERCULES INCORPORATED (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205726-A1 | Ester derivatives and medical use thereof | MTTP, LIPC, CETP | SRC 3252/4885CYP2D6 1011/4885LMNA 2938/4885 |
| US-20050075367-A1 | Ester compound and medicinal use thereof | LIPC, CES1, MTTP | SRC 2971/4885CYP2D6 752/4885LMNA 2248/4885 |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | LIPC, CES1, MTTP | SRC 2497/4885CYP2D6 705/4885LMNA 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.