Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679983 | 0.85 | TMEM97 (0.38) | TMEM97SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL11554624 | 0.79 | CYP1A2 (0.43) | TMEM97SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL11797650 | 0.78 | TMEM97 (0.33) | TMEM97SIGMAR1KCNH2 | |
| SCHEMBL11798123 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL11751988 | 0.75 | SIGMAR1 (0.54) | TRPV1SIGMAR1 | |
| SCHEMBL23731783 | 0.70 | TMEM97 (0.50) | TMEM97SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL16363451 | 0.68 | TMEM97 (0.44) | TMEM97SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL11677856 | 0.68 | HTT (0.39) | SIGMAR1KCNH2KMT2AKDM4E | |
| SCHEMBL11801336 | 0.67 | HDAC1 (0.38) | TRPV1 | |
| SCHEMBL14731739 | 0.67 | SIGMAR1 (0.69) | TMEM97SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |